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淋巴细胞微核检测在恶性滋养细胞肿瘤化疗监测中的应用(附12例报告) 被引量:1

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摘要 我们采用外周血淋巴细胞微核检测,对12例恶性滋养细胞肿瘤化疗患者进行动态监测,观察微核率变化与化疗方案、化疗反应及疗效的关系。结果:化疗反应中,重度者及5-FU+KSM方案化疗者,化疗后微核率均有增加,以化疗第7天最为明显(P均<0.05)。表明外周血淋巴细胞微核率变化与化疗后体细胞损伤以及抗癌药物作用机理可能有关,值得进一步探讨。
出处 《福建医药杂志》 CAS 1998年第2期25-26,共2页 Fujian Medical Journal
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