消化性溃疡药物与心理治疗的对比观察

A COMPARATIVE STUDY OF THE THERAPEUTIC EFFECTS OFDRUG AND PSYCHOLOGY ON GASTRIC ULCER

目的：药物与心理治疗１１８例活动性消化溃疡的疗效观察。方法：将胃镜证实资料完整的活动性消化溃疡病人随机分为三组：药物组（Ｍ组）４５例，心理治疗组（Ｐ组）２２例，药物＋心理治疗组（Ｍ＋Ｐ组）５１例，均以４周为一疗程。疗程结束时６个月和１２个月分别复查胃镜。结果：Ｍ组、Ｐ组、Ｍ＋Ｐ组溃疡愈合率分别为９３．３３％、４０．９１％、９８．０４％。Ｍ＋Ｐ组与Ｍ组比较，差异无显著意义（Ｐ＞００５）；Ｍ组和Ｍ＋Ｐ组均高于Ｐ组，有显著性差异（Ｐ＜００５）。６个月溃疡积累复发率分别为２３．８０％、３３．３３％、０；１２个月溃疡积累复发率分别为４０．４８％、５５．５５％、２％；Ｍ组积累复发率低于Ｐ组，差异无显著性（Ｐ＞００５）；Ｍ＋Ｐ组积累复发率明显低于Ｍ组和Ｐ组，有显著性差异（Ｐ＜００５）。结论：药物加心理治疗消化性溃疡复发率低，值得推广应用。

Objective:Therapeutic effects of drug therapy and psychotherapy on 118 cases of active gastric ulcer were analyzed.Methods: 118 cases of active gastric ulcer idendified with gastroscope were divided into three groups.45 cases in drug therapy group(M),22 in psychotherapy group(P) and other 51 in combined therapy group (M+P),with the average treatment course of four weeks.Gastroscopic reexamination was offered to the patients immediately after the treatment course at six and twelve months respectively.Results:The cure rates were 93.33%,40.91% and 98.04% respectively in group M,P and M+P. The differense of cure rate of group M+P and group M were not significant (P>005).The cure rates of group M and group M+P were both higher than that of group P,and the difference was significant (P<005).The cumulative recurrence rates at six months were 23.80%,33.33% and O in group M,P and M+P respectively,but were 40.48%, 55.55% and 2% respectively at twelve months.The cumulative recurrence rate of group M was lower than that of group P,without significant difference (P>005);while the cumulative recurrence rate of M+P was obviously lower than that of group M and group P and the difference was significant (P<005)。Conclosion:With better therapeutic effect on gastric ucler and lower recurrence rate,combined drug therapy and psychotherapy had proved to be a sound approach for the treatment of gastric ucler,thus worth being recommended and applied.