摘要
目的：观察盐酸吡硫醇治疗多发性神经病（polyneuropathy）的临床疗效方法：将80例多发性神经病病人随机分成2组,治疗组40例,在常规治疗基础上加用注射盐酸吡硫醇剂量0.4/d,对照组40例,为常规治疗组,在针对病因治疗基础上给予VitB1100mg/d,VitBl2500ug/d肌注,ATP40mg/d和肌苷10mg/d静滴,胞二磷胆碱注射液0.5g/d静滴14天为一疗程。同期观察两组病人临床表现和肌电图的改善情况。结果：治疗组有37例好转,对照有30例好转。行卡方检验,P≤0.05,有显著差异性。肌电图恢复情况,治疗组有38例恢复对照组有31例恢复。行卡方检验,P≤0.05有显著差异性。结论：盐酸吡硫醇治疗多发性神经病疗效确切,值得深入研究。
Objective： To observe the clinical effect of pyritinol hydrochloride in the treatment of polyneuropathy. Method： 80 patients with polyneuropathy were randomly divided into two groups. Treatment group （40 cases） were added 0.4/d of pyritinol hydrochloride on the basis of conventional treatment, while concrol group （40 cases） was given VitB1 100mg/d and VitB12 500ug/ d for intramuscular injection, ATP 40mg/d and inosine 10mg/d for intravenous dropping, and citicoline injection 0.5g/d for intravenous dropping. 14 days was a period course. The clinical manifestation and improvement situations of electromyography in two groups were observed. Result： In treatment group, 37 cases were improved, while in control group, 30 cases were improved. P≤0.05 by the way of chi--square test, the difference was significant. 38 cases in treatment group and 31 cases in control group were recovered in electromyography, P≤0.05, the difference was significant. Conclusion： The treatment of polyneuropathy with pyritinol hydrochloride has exact effect, which is worth further study.
出处
《内蒙古中医药》
2009年第3期33-35,共3页
Inner Mongolia Journal of Traditional Chinese Medicine
