摘要
目的比较西酞普兰和氟西汀治疗老年抑郁症的疗效及安全性。方法将70例老年抑郁症患者随机分为西酞普兰组和氟西汀组。疗程6周。采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)及治疗中出现的症状量表(TESS)评定疗效和不良反应。结果两组总体疗效相仿,两组减分率无显著性差异,西酞普兰组不良反应较轻,安全性好。结论西酞普兰是一种安全有效的抗抑郁药,可用于老年抑郁症患者。
Objective To compare the efficacy and safety of citalopram and fluoxetine in the treatment of senile depression.Methods Seventy patients with senile depression were randomly divided into citalopram group and fluoxetine group.The period of experiment was six weeks.The efficacy and side effects were evaluated by Hamilton depressive scale（HAMD）,Hamilton anxiety scale（HAMA） and treatment emergent symptom scale（TESS）.Results Effects of two groups were similar.No significantly difference in the reductive rates was found between two groups.The side effects were less in citalopram groups.Conclusion Citalopram is an effective and safe antidepressant in the treatment of senile depression.
出处
《中国健康心理学杂志》
2009年第1期107-108,共2页
China Journal of Health Psychology
