超早期手术结合川芎嗪治疗高血压脑出血的临床研究

The Clinical Study of Ultra-early Surgical Treatment Combined with Ligustrazine Hypertensive Cerebral Hemorrhage

目的:寻求能够提高高血压脑出血临床疗效的救治方案。方法:采用随机对照试验方法对72例高血压脑出血患者进行分组治疗研究。治疗组32例,采用中西医结合方案(包括超早期手术,常规西医西药及中药川芎嗪注射液静脉滴注等综合救治方案);对照组40例,采用手术,常规西医、西药治疗。连续治疗28d后进行疗效评定。结果:治疗组临床疗效明显优于对照组(χ2=4.15,P<0.05),患者死亡数明显减少,差异有显著性(χ2=8.04,P<0.05);并发症发生数治疗组少于对照组(肺部感染6:16,χ2=11.37,P=0.001;上消化道出血8:16,χ2=4.10,P=0.04)。结论:超早期手术结合中药治疗高血压脑出血疗效较不用中药组为好。

Objective. To look for an effective treatment for hypertensive intracerebral hemorrhage. Methods.By the method of random and control, patients with hypertensive inftacerebral hemorrhage were randomly divided into two groups： The treatment group（32 patients）was treated with ntegrated traditional Chinese and western medicine therapy, including super-early operation, conventional western medicine and Chuanxiongqin injection treatment. The control group（40 patients）was treated with operation and conventional western medicine treatment. The effect was evaluated on 28th day after treatment. Results：The effect of the treatment group was superior to that of the control group（χ^2 =4. 15,P〈0.05）the treatment group had lower mortality rate（χ^2 = 8.04, P〈0. 05） and lover morbidity of complications （pulmonary infection： 6/16 cases, χ^2 = 11.37, P = 0. 001 ; upper-congestive hemorrhage： 8/16 cases, χ^2 = 4. 10, P = 0. 04）, statistical data indicated that there was significantdifference between treatment group and control group. Conclusion. Super-early operation with traditional Chinese medicine in treatment of hypertensive intracerebral henorrhage has a better effect than the treatment without traditional Chinese medicine.