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创伤后应激障碍脑功能影像研究进展 被引量：2

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摘要 创伤后应激障碍（post—traumatic stress disorder，PTSD）是少数具有相对明确病因的精神障碍之一，是指经历突发性、威胁性或灾难性生活事件后，导致个体即时或延迟出现的创伤后心理失衡状态，其临床症状包括闯入式记忆、闪回和心理性健忘症（APA），严重时会出现人格解体。
作者 王淑珍 王芳
机构地区 西北大学南校区公共管理学院 三原县人民医院
出处 《中华医学杂志》 CAS CSCD 北大核心 2009年第21期1505-1508,共4页 National Medical Journal of China
关键词 创伤后应激障碍 影像研究 脑功能 精神障碍 生活事件 心理失衡 临床症状 人格解体
分类号 R686 [医药卫生—骨科学]
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参考文献26

  • 1Dickie EW, Brunet A, Akerib V, et al. An fMRI investigation of memory encoding in PTSD: Influence of symptom severity. Neuropsychologia, 2008, 46: 1522-1531.
  • 2Turnbull GJ. The biology of post-traumatic stress disorder.Psychiatry, 2006, 5: 221-224.
  • 3Whalley MG, Rugg MD, Smith APR, et al. Incidental retrieval of emotional contexts in post-traumatic stress disorder and depression: an fMRI study. Brain Cogn, 2009, 69: 98-107.
  • 4Lanius RA, Williamson PC, Hopper J, et al. Recall of emotional states in posttraumatic stress disorder: an fMRI investigation. Biol Psychiatry, 2003, 53: 204-210.
  • 5Armony JL, Corbo V, Clement MH, et al. Amygdala response in patients with acute PTSD to masked and unmasked emotional facial expressions. Am J Psychiatry, 2005, 162: 1961-1963.
  • 6Astur RS, Germain SAS, Tolin D, et al. Hippocampus function predicts severity of post-traumatic stress disorder. Cyberpsychol Behav, 2006, 9: 234-240.
  • 7Geuze E, Vermetten E, Ruf M, et al. Neural correlates of associative learning and memory in veterans with posttraumatic stress disorder. J Psychiatr Res, 2008, 42 : 659- 669.
  • 8Werner NS, Meindl T, Engel RR, et al. Hippocampal function during associative learning in patients with posttraumatic stress disorder. J Psychiatr Res, 2009, 43:309-318.
  • 9Kim MJ, Chey J, Chung A, et al. Diminished rostral anterior cingulate activity in response to threat-related events in posttraumatic stress disorder. J Psychiatr Res, 2008, 42 : 268- 277.
  • 10Shin LM, Wright CI, Cannistraro PA, et al. A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraurnatic stress disorder. Arch Gen Psychiatry, 2005, 62: 273 -281.

同被引文献17

  • 1JovanovicT, SakomanAJ, Kozari?-Kova?i?D, et al. Acute stress disorder versus chronic posttraumatic stress disorder: inhibition of fear as a function of time since trauma[J]. Depress Anxiety,2013,30(3):217–224. DOI:10.1002/da.21991.
  • 2IsserlinL,ZerachG,SolomonZ. Acute stress responses: A review and synthesis of ASD, ASR, and CSR[J]. Am J Orthopsychiatry, 2008, 78(4): 423–429. DOI: 10.1037/a0014304.
  • 3ChenL,LuiS,WuQZ,et al. Impact of acute stress on human brain microstructure: An MR diffusion study of earthquake survivors[J]. Hum Brain Mapp, 2013, 34(2): 367–373. DOI: 10.1002/hbm.21438.
  • 4DuMY,LiaoW,LuiS,et al. Altered functional connectivity in the brain default-mode network of earthquake survivors persists after 2 years despite recovery from anxiety symptoms[J]. Soc Cogn Affect Neurosci, 2015, 10(11): 1497–1505. DOI: 10.1093/scan/nsv040.
  • 5LuiS,HuangX,ChenL,et al. High-field MRI reveals an acute impact on brain function in survivors of the magnitude 8. 0 earthquake in China[J]. Proc Natl Acad Sci U S A, 2009, 106(36): 15412–15417. DOI: 10.1073/pnas.0812751106.
  • 6TomasiD,VolkowND. Functional connectivity density mapping[J]. Proc Natl Acad Sci U S A, 2010, 107(21): 9885–9890. DOI: 10.1073/pnas.1001414107.
  • 7CardinalRN,ParkinsonJA,HallJ,et al. Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex[J]. Neurosci Biobehav Rev, 2002, 26(3): 321–352. DOI: 10.1016/S0149-7634(02)00007-6.
  • 8FrijlingJL,ZuidenMV,KochSB,et al. Intranasal oxytocin affects amygdala functional connectivity after trauma script-driven imagery in distressed recently trauma-exposed individuals[J]. Neuropsychopharmacology, 2015, 41(5):1286–1296. DOI: 10.1038/npp.2015.278.
  • 9AchesonDT,GresackJE,RisbroughVB. Hippocampal dysfunction effects on context memory: possible etiology for posttraumatic stress disorder[J]. Neuropharmacology, 2012, 62(2): 674–685. DOI: 10.1016/j.neuropharm.2011.04.029.
  • 10KleimB,EhlersA. Reduced autobiographical memory specificity predicts depression and posttraumatic stress disorder after recent trauma[J]. J Consult Clin Psychol, 2008, 76(2): 231–242. DOI: 10.1037/0022-006X.76.2.231.

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中华医学杂志
2009年 第21期

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