摘要
目的:探讨腹腔镜手术与曲谱瑞林联合治疗Ⅳ期子宫内膜异位症(EM)的最优方式。方法:对62例Ⅳ期EM患者行回顾性分析,32例于腹腔镜术后肌注曲谱瑞林,3.75mg,每月1次,连续3月;30例先使用3个月曲谱瑞林后再手术,用法同前。比较二者围手术期情况和远期预后。结果:两组手术时间分别为(126±29)min和(79±26)min,出血量为(390±32)ml和(180±60)ml,差异均有显著性(P〈0.05)。随访2~5年,其妊娠率、复发率及盆腔疼痛缓解率差异均无显著性(P〉0.05)。结论:与术后使用GnRH—a类药物相比,腹腔镜手术前用药疗效相似,但更有利于手术的实施。
Objective:To compare the curative effects of triptorelin before and after laparoscopic surgery in treatment of stage Ⅳ endometriosis. Methods: A retrospective study was conducted on 62 patients with stage Ⅳ endometriosis, 32 managed with triptorelin preoperatively and another 30 postoperatively, both at the same dosage of 3.75 mg by intramuscular injection monthly for 3 months. Mean operative duration, mean blood loss, pregnancy rates, recurrence rates and pain relieving rates were recorded and compared between the two groups. Results: Mean operative durations for the two groups were ( 126 ± 29 ) min and ( 79± 26 ) min respectively, with significant difference, and the volumes of mean blood loss were ( 390 ± 32 ) ml and ( 180 ± 60 ) ml, respectively, with significant difference between them as well (P 〈 0. 05) . For the two to five years of follow - up, no differences between them were found in respect of pregnancy rate, recurrence rate and pain relieving rate (P 〉 0.05 ). Conclusion: Compared with injection of triptorelin after laparoscopic operation in the treatment of stage Ⅳ endometriosis, administration of triptorelin before that operation appears also effective, and it can facilitate subsequent surgical manipulation.
出处
《西北国防医学杂志》
CAS
2009年第3期196-198,共3页
Medical Journal of National Defending Forces in Northwest China
基金
广州科技计划项目基金资助项目(2008J1-C131)