摘要
目的研究乳康平胶囊对SD大鼠乳腺增生模型中肝脏、乳腺中微量元素的影响。方法实验分为空白组、模型组、乳康平组,逍遥丸组和三苯氧胺组。取各动物的肝脏、乳腺,经消化处理后测定铜(Cu)、锌(Zn)、铁(Fe)、锰(Mn)、硒(Se)变化情况。结果与模型组比较,各治疗组动物肝脏和乳腺中微量元素的变化均有显著性差异,能改善乳腺增生大鼠肝脏和乳腺中失调的微量元素含量。结论乳康平胶囊可有效地调节乳腺增生大鼠肝脏和乳腺中的微量元素。
Objective To study the effects of Rukangping Capsules （RC） on trace elements in liver and breast of mammary gland hyperplasia rats. Methods SD rats were divided into blank group, model group, RC group, Xiaoyao pills group and tamoxifen group. The changes of content of copper （Cu）, zinc（Zn）, iron （Fe）, manganese （Mn）, selenium （Se） in liver and breast were observed. Results Compared with the model group, the hepatic and mammary trace element content were improved in the three medication groups and the difference being significant. Conclusion RC can regulate the trace elements content in liver and breast of mammary gland hyperplasia rats.
出处
《中药新药与临床药理》
CAS
CSCD
北大核心
2009年第3期228-230,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
河北省科技支撑项目(07276709D)
河北省卫生厅项目(05045)
关键词
乳康平
SD大鼠
乳腺增生
微量元素
肝脏
乳腺
Rukangping capsules
SD rat
Hyperplasia of mammary glands
Trace element
Liver
Breast
