逍遥泡腾片的质量标准研究

Study on the Quality Standard of Xiaoyao Effervescent Tablets

目的建立逍遥泡腾片的质量标准。方法采用薄层色谱法(TLC)鉴别方中的白芍、当归、柴胡、甘草,采用高效液相色谱法(HPLC)测定白芍中芍药苷的含量。结果TLC法可检出白芍、当归、柴胡、甘草,斑点清晰,阴性对照无干扰,专属性强。芍药苷在0.082～1.025μg范围内线性良好(r=0.9994),平均加样回收率为100.44%,RSD为2.37%。结论该方法简便、可靠、准确,可用于逍遥泡腾片的质量控制。

Objective To establish the quality standard for Xiaoyao Effervescent Tablets. Methods Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Bupleuri and Radix Glycyrrhizae in the tables were identified by TLC. Paeoniflorin content was determined by HPLC. Results Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Bupleuri and Radix Glycyrrhizae could be identified by TLC, and the identification was highly specific without interference. The linear range of paeoniflorin was 0. 082 μg - 1. 025 μg. The average recovery was 100.44 % （RSD =2.37 % ）. Conclusion The method is simple, reliable, and accurate, and can be used for the quality control of Xiaoyao Effervescent TabLets.