肝移植患者术后感染与降钙素原关系探讨

Procalcitonin in liver transplantation patients and its correlation with post-operative infections

[目的]探讨血清降钙素原(PCT)在肝移植术后并发感染诊断中的临床意义。[方法]用免疫比浊法定量检测54例肝移植患者血清中的PCT和C反应蛋白(CRP),观察两指标在无并发症患者和并发感染患者中的水平及阳性率。[结果]PCT对肝移植术后17例并发感染的诊断敏感性和特异性均为100%,明显优于CRP(P<0.01)。[结论]血清PCT对肝移植术后并发感染的诊断有重要价值。

[ Objective] This study explores the diagnostic value of proealcitonin （PCT） as an indicator for liver transplantation patients with post -operative infection. [ MethodsI Serum levels of PCT and C -reactive protein （CRP） were quantitatively measured in 54 patients who underwent liver transplantation with immunoturbidimetry. Their infection incidents were recorded. Levels and positive rates of PCT and CRP were detected in liver transplantation patients with post - opera-tive infection or non -infection. [ Results] Serum level of PCT increased significantly in 17 liver transplantation patients with post - operative infection as compared with that in the non - infection patients. Both sensitivity and specificity of PCT were 100%, which were significantly difference from those of serum level of CRP （P 〈0.01 ）. [ Conelusion] Serum level of PCT has important value in the diagnosis of postoperative infection of liver transplantation patients.