儿童格林-巴利综合征52例临床分析

Analysis of 52 children patients with Guillain-Barre syndrome

目的:探讨儿童格林-巴利综合征(GBS)的临床特点以及综合治疗效果。方法:回顾性分析1997年1月～2007年12月在遂宁市中心医院住院治疗的儿童GBS52例患儿的临床资料。结果:52例患儿中多以四肢对称性迟缓性软瘫以及颅神经和自主神经功能损害为主要表现,结合临床表现及电生理检查进行早期确诊以及使用血浆置换或免疫球蛋白静脉滴注等综合治疗对该病的预后具有很大的作用。结论:GBS临床表现复杂多样,病情发展快,易误诊、应引起足够的重视。

Objective ：To explore the clinical characters and comprehensive therapeutic efficacy of Guillain-Barre syndrome. Methods：To retrospectively analyze the clinical data of 52 hospitalized children with Guillain-Barre syndrome in the Central Hospital of Suining from January 2001 to December 2007. Results ：The main clinical manifestations were symmetrically and flabbily flaccid paralysis of limbs and function impairment of cranial nerves and autonomic nerves in 52 sick children. The combined therapy such as earlier period final diagnosis combining clinical manifestations and electrophysiological examination,blood plasma substitution or intravenous drip with immunoglobulin was greatly useful to prognosis. Conclusion ：The clinical manifestations of Guillain-Barre syndrome are complicated and diverse ,the progression of Guillin-Barre syndrome is rapid and it is easy to misdiagnose,thus it should be enough emphasized.