间歇低氧训练对SD大鼠血液流变学指标的影响

Effect of Intermittent Hypoxic Training on Hemorheology in Rats

目的观察间歇低氧训练对血液流变学的影响。方法选用64只Sprague-Dawley大鼠为实验对象,随机分为4组:对照组(C组)、间歇低氧训练组(I组)、游泳训练组(S组)和间歇低氧+游泳训练(IS)组,分别进行4周的间歇低氧训练(I组)、游泳训练(S组)及间歇低氧+游泳训练(IS组),观察SD大鼠的血液流变学指标的变化。结果3种干预方式对SD大鼠血液流变学指标均有不同程度的影响,红细胞压积、全血粘度、血浆粘度及红细胞聚集指数均高于对照组,其中间歇低氧训练+游泳训练组对各项指标的影响最为显著。结论提示间歇低氧训练通过促进红细胞数量、改善机体有氧能力的同时,血流阻力也随之增加,对机体产生不利影响。

The purpose of this paper is to observe the effect of intermittent hypoxic training on hemorheology in rats.64 Sprague - Dawley rats are random divided into 4 goups： C： control group, I： intermittent hypoxic training group, S： swimming training group and IS： intermittent hypoxic training ＋ swimming training group. Four weeks later beside, BV, PV, Hct and RCA of I,S,and IS groups become higher than C group. Especially the parameters of IS group are significantly higher than that of C group. It can be concluded that intermittent hypoxic training can promote the creation of red blood cell, but simultaneously some bad effects occurred.