摘要
目的比较加替沙星与左氧氟沙星治疗敏感性细菌引起的泌尿系统感染的疗效及安全性。方法将60例泌尿系统感染患者随机均分为两组,加替沙星组(A组)30例给予加替沙星0.2g/次,左氧氟沙星组(B组)给予左氧氟沙星0.2g/次,均以5%葡萄糖注射液稀释后静脉滴注,每日2次,疗程为7～10d。结果A组和B组临床总有效率分别为96.67%和80.00%(P<0.05),细菌清除率分别为90.00%和80.00%(P<0.01),不良反应发生率分别为6.67%和10.00%。结论加替沙星治疗泌尿系统感染疗效确切,安全性高。
Objective To evaluate the clinical efficacy and safety of gatifloxacin in the treatment of urinary tract infection. Methods 60 patients with urinary tract infection were randomly and equally divided into group A（30 cases） and Group B（30 cases）, receiving intravenous dripping of gatifloxaein or levofloxacin 0. 2 g, b. i. d., for 7 d- 14 d respectively. Results The total effective rate of gatifloxaein group and levofloxacin group was 96.67% and 80. 00% respectively（ P 〈 0. 05）, the bacterial clearance rate was 90.00% and 80.00% （P 〈 0.01 ） respectively. And the incidence of adverse reactions was 6.67% and 10.00% respectively. Conclusion Gatifloxacin is safer and more effective for treating urinary tract infection.
出处
《中国药业》
CAS
2009年第11期62-63,共2页
China Pharmaceuticals
关键词
加替沙星
左氧氟沙星
泌尿系统感染
随机对照试验
gatifloxacin
levofloxacin
urinary treat infection
randomized controlled trial
