脑内多发性硬化的MRI诊断

MRI Diagnosis of Intracerebral Multiple Sclerosis

目的：回顾性分析多发性硬化的ＭＲＩ特征及其对诊断与鉴别诊断的价值。材料和方法：经本院临床和随访确诊为ＭＳ的５０例患者，均行常规头颅ＭＲＩ检查，采用普通ＳＥ序列Ｔ１ＷＩ和Ｔ２ＷＩ。３６例继续行钆剂增强后ＳＥＴ１Ｗ扫描和磁化传递成像（ＭＴＩ）。结果：５０例患者脑实质内均见斑片状病灶。多数病灶位于双侧脑室旁白质及半卵圆区（４２例），其次为脑干、小脑（１４例），少数在颞叶、岛叶及顶枕叶（３例）。胼胝体轻度萎缩（１４例）及不同程度的脑萎缩（１５例）。增强后轻度强化及斑点状强化（２０例）。结论：脑内多发性硬化有较典型的ＭＲＩ表现。

urpose:To review the diagnosis and differential diagnosis of the MRI features in multiple sclerosis. Materials and methods: Fifty cases of clinically confirmed multiple sclerosis were examined by MRI.Conventional SE Pulse sequence T1WI and T2WI.GD-DTPA enhancement and MTI were carried out in 36 cases. Results: In all cases patchy lessions can be seen in cerebral medulla and most lessions (42 cases) were located in the bilateral periventricular and the centrum semiovales, some lessions can be seen in brain stem and cerebellum (14 cases),in temporal, insular and paritooccipital lobes (3 cases) with slight atrophy of corpus acllosum (14 cases)and varous degree of cerebral atrophy (15 cases).slight enhancement with patchy appearance injection occurred after intravenous contrast medium. Conclusion: Intracerebral multiple sclerosis has the characteristic changes in MR imaging. According to clincal manifestation, it is possible to make the diagnosis.