白英的化学成分(英文)

Chemical Constituents from Solanum lyratum

目的:研究白英Solanum lyratum Thunb.全草的化学成分。方法:采用正相、反相硅胶柱色谱及Sephadex LH-20凝胶柱色谱和制备薄层等手段进行分离纯化, 通过波谱解析和理化鉴别进行结构鉴定。结果:分离鉴定出 11个化合物, 分别为薯蓣皂苷元(1)、剑麻皂苷元(2)、丁香醛(3)、丁香酸(4)、对羟基苯甲醛(5)、莨菪亭(6)、N-顺式阿魏酰基酪胺(7)、β-谷甾醇(8)、胡萝卜苷(9)、赤藓糖醇(10)、甘露醇(11)。结论:化合物 7 为首次从茄科植物中分离得到, 化合物10、11为首次从茄属植物中分离得到, 化合物 3-5 为首次从该植物中分离得到。

AIM： To study the chemical constituents of the whole plant of Solanum lyratum. METHODS： The compounds were isolated by column chromatography over silica gel and RP-C18, and purified by Sephadex LH-20 and preparative TLC. Their structures were elucidated on the basis of physicochemical property and spectral data. RESULTS： Eleven compounds were isolated and identified as： diosgenin （1）, tigogenin （2）, syringaldehyde （3）, syringic acid （4）, 4-hydroxybenzaldehyde （5）, scopoletin （6）, N-cis-feruloyltyramine （7）, β-sitosterol （8）, daucosterol （9）, erythritol （10） and mannitol （11）. CONCLUSION： Compound 7 has been separated from Solanaceae plant for the first time, compounds 10 and 11 have been isolated from Solanum plant for the first time, and compounds 3-5 have been obtained from this plant for the first time.