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膀胱癌经尿道电切除术后吡柔比星膀胱灌注预防复发的临床观察

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摘要 目的探讨膀胱灌注吡柔比星(THP)预防浅表性膀胱癌术后复发的安全性及疗效。方法对83例浅表性膀胱癌患者行经尿道膀胱肿瘤电切术(TURBT),术日及术后1周开始用THP(30mg/40ml)进行膀胱内定期灌注,每次药物在膀胱内保留30～60min,每周1次,连续8次,以后每月1次,连续10次,并随访18～45个月。结果83例患者均未见明显全身性药物不良反应,仅15例出现轻微膀胱刺激症状。结论膀胱灌注THP预防浅表性膀胱癌术后复发的疗效确切,不良反应小,安全性好,是较理想的膀胱灌注化疗药物。
作者 王海学 管建云 李守淼 刘国华 白东晓
机构地区 安阳市肿瘤医院外三科
出处 《医学信息（内.外科版）》 2009年第4期373-374,共2页 Medical Information Operations Sciences Fascicule
关键词 膀胱肿瘤 吡柔比星 膀胱灌注化疗
分类号 R737.14 [医药卫生—肿瘤]
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医学信息（内.外科版）
2009年 第4期

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