3Chatzidakis K,Goulas A,Athanassiadou-Piperopoulou F,et al.Methylenete trahydrofolate reductase C677T poly-morphism:association with risk for childhood acute lymphoblastic leukemia and response during the initial phase of chemotherapy in Greek patients[J].Pediatr Blood Cancer,2006,47(2):147-151.
1Harris NL,Jaffe ES, Diebold J, et al. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee Meeting-Airlie House, Virginia, November 1997 [ J]. J Clin Oncol, 1999,17 ( 12 ) : 3835-3 849.
6Kim YI,Pogribuy IP,Basnakian AG,et al.Folate deficiengcu in ratsinduces DNA strand breaks and hypomethylation within the p53 tumor suppressdor gene[J].Am J Clin Nutr,1997,65:46-52
7Choi SW,Kim YI,Weitzel JN,et al.Folate depletion impairs DNA excision repair in the colon of the rat[J].Gut,1998,43:93-99
8Skibola CF,Smith MT,Kane E,et al.Polymorphisms in the m-ethylemete trahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults[J].Proc Natl Acad Sci USA,1999:12810-12815
9Matthews JH,Shiels S,Wickramasinghe SN,et al.The effects of folate deficiency on thymidylate synthetase activity,deoxyuridine suppression,cell size and doubling time in a cultured human myeloid cell line[J].Eur J Haematol,1990,45:43-47
10Blount BC,Mack MM,Wehr CM,et al.Folate deficiency cause uracilmisinorporation into human DNA and chromosome breakage:implications for cancer and neuronal damage[J].Proc Natl Acad Sci USA,1997,94:3290-3295
