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脑卒中后认知功能障碍相关因素分析 被引量:7

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摘要 目的:探讨脑卒中(以下简称卒中)后认知功能障碍发生的相关危险因素。方法:连续选取急性脑卒中患者155例,依据智能评估结果分:认知正常对照组、血管性认知障碍无痴呆(CIND)组及血管性痴呆(VD)组;分别行生化、胸片、心电图、头颅CT/MRI检查及相关神经心理量表检查。结果:卒中后有认知功能损害者呈高龄、低文化水平,血管性危险因子、卒中次数、内科并发症比认知正常组增多(P<0.05,P<0.01),影像显示左侧病灶,病灶大小、脑萎缩、脑白质病变、陈旧/静息病灶数目和对照组比较,差异有统计学意义(P<0.01,P<0.05),急性期及3个月后斯堪的纳维亚卒中量表(SSS),简易精神状态量表(MMSE),日常生活能力(BI)评分各组间均有明显差异(P<0.01)。结论:血管性危险因子在卒中后认知障碍者更普遍,陈旧病灶/静息病灶数目、神经功能缺损的程度是卒中后3个月发生痴呆的强烈预测因子。
出处 《广西医科大学学报》 CAS 2009年第2期234-236,共3页 Journal of Guangxi Medical University
基金 广西壮族自治区卫生厅自筹资金科研项目(Z2005207)
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  • 1Ott A, Breteler MM, Van Harskamp F, et al. Incidence and risk of dementia: the Rotterdam Study [J]. Am J Epidemiol, 1998, 147:574-580.
  • 2Hebert R, Lindsay J, Verreault R. Vascular dementia: incidence and risk factors in the Canadian study of health and aging [ J ]. Stroke,2000, 31 : 1487-1493.
  • 3Di Carlo A, Baldereschi M, Amaducci L. Incidence of dementia,Alzheimer' s disease and vascular dementia in Italy. 'Ihe ILSA Study[J] .J Am Geriatr Soc,2002,50:41-48.
  • 4Knopman DS, Rocca WA, Cha RH. Incidence of vascular dementia in Rochester, Minn, 1985-1989 [J]. Arch Neurol, 2002, 59: 1605-1610.
  • 5Yoshitake T, Kiyohara Y, Kato I, et al. Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayarna Study [J]. Neurology, 1995, 45:1161-1168.
  • 6Brayne C, Gill C, Huppert FA. Incidence of clinically diagnosed subtypes of dementia in an elderly population : Cambridge Project for Later Life [J]. Br J Psychiatry, 1995,167:255-262.
  • 7Posner HB, Tang MX, Ialchsinger J The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function [J].Neurology, 2002, 58 : 1175-1181.
  • 8Haan MN, Mungas DM, Gonzalez HM. Prevalence of dementia in older Latinos: the influence of type 2 diabetes mellitus, stroke and genetic factors [J]. J Am Geriatr Soc,.2003,51:169-177.
  • 9O' Brien JT, Erkinjuntti T, Reisberg B, et al. Vascular cognitive impairment. Lancet Neurol, 2003, 2:89-98.
  • 10Bowler JV, Munoz DG, Merskey H, et al. Fallacies in the pathological conilrmation of the diagnosis of Alzheimer's disease. J Neurol Neurosurg Psychiatry, 1998, 64 : 18-24.

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