一氧化碳中毒后迟发性脑病的CT特征

CT Feature of Delayed Encephalopathy After Carbon Monoxide Intoxication

目的：评价ＣＯ中毒后迟发性脑病的ＣＴ使用价值。材料方法：回顾分析４６例ＣＯ中毒后迟发性脑病的ＣＴ表现。结果：迟发性脑病发病前的中间清醒期为４～１０４天（１～３周，占６９９％）。发病年龄２４～７８岁（平均５３２岁）。４６例中最常见的ＣＴ表现是脑白质密度减低；双侧对称性额叶Ｕ形纤维低密度灶可长期存在；迟发性脑病发生时脑白质密度减低往往加重；额叶Ｕ形纤维低密度灶发生率与本病发生率相关；双侧苍白球低密度灶发生率与本病发生率无明显关系；脑萎缩的迅速加重是急性ＣＯ中毒后迟发性脑病的后果之一。结论：ＣＴ对指导急性ＣＯ中毒后迟发性脑病的预后和治疗十分有效。

PURPOSE:To evaluate the value of using CT for delayed encephalopathy after carbon monoxide (CO) intoxication. MATERIALS AND METHODS:CT images obtained in 46 patients with delayed encephalopathy after acute CO intoxication were reviewed. RESULT:The lucid interval before appearance of delayed encephalopathy varied from 4-104 days (1-3 weeks,69 9%). Ages ranged from 24-78 years(mean 53 2 years).The most frequent CT finding,seen in 46 cases,was decreased density in the cerebral white matter, and the symmetric,bilateral low-density regions in subcortical U fibers of the frontal lobes existed in a long-term. Decreased density in the cerebral white matter became seriously while the delayed encephalopathy happened. The incidence of the low-density regions in the subcortical U fibers of the frontal lobes had relevancy to the incidence of delayed encephalopathy. There was not relevance between the incidence of the low-density lesions in the globus pallidus balaterally and the incidence of delayed encephalopathy. It was effective that the appearance of the hippocampus uncus lesion through the section of superior sella cistern and the cerebral cortex lesion made use of CT. The cerebral atrophy rapidly worsened was one of the consequences of delayed encephalopathy after acute CO intoxication. CONCLUSION:CT for pointing out the prognosis and treatment of the delayed encephalopathy after acute CO intoxication are relatively effective.