女性消化性溃疡6037例的临床特点分析

Analysis on clinical characteristics of 6037 cases of female peptic ulcer

目的探讨女性消化性溃疡的临床表现特点。方法对南宁市17家医院1992～1997年间经胃镜检查诊断为消化性溃疡的6037女性病例进行回顾性分析。结果（1）共行胃镜检查的104121例,检出女性消化性溃疡6037例,占检出消化性溃疡的24.89%,其中十二指肠溃疡患者5308例,胃溃疡590例,复合性溃疡134例,食管溃疡5例;分别占女性例数的84.16%、9.35%、2.22%和0.08%（P〈0.01）。（2）溃疡部位数共计7187处,其中分布十二指肠6271处（87.25%）、胃911处（12.68%）、食管5处（0.07%）。（3）胃溃疡的发病部位以胃窦部（440处,48.30%）常见,十二指肠溃疡则以前壁多见（3082处,49.14%）,霜斑样溃疡在十二指肠球后发生率较高。（4）发病人群主要集中在20～59岁的中青年,占全部患者的86.80%。随年龄增长,复合性溃疡的发生率逐渐升高,十二指肠溃疡发生率逐渐减少。（5）检出溃疡部位数是冬季〉春季〉秋季〉夏季,冬春季与夏秋季比较差异有统计学意义（P〈0.05）。结论女性溃疡以十二指肠溃疡多见,球部为十二指肠溃疡的高发部位,霜斑样溃疡在十二指肠球后较常见;胃溃疡的发病部位以胃窦部常见。溃疡以中青年多发,冬春季溃疡检出明显高于夏秋季。

Objective To find out the clinical characteristics of female peptic ulcer disease.Methods The analysis of 6037 cases of female peptic ulcer from 17 hospitals in Nanning during 1992～1997 were performed.Results（1） Among all the cases,5308（84.16%）cases were duodenal ulcers,590（9.35%） cases were gastric ulcer,134（2.22%）cases were compound ulcers,5（0.08%）cases were esophageal ulcer.（2）The total sites of ulcer were 7187 sites,of them 6271（87.25%）sites were found in duodenal,911（12.68%） sites were found in stomach,5（0.07%） sites were found in esophagus.（3）Gastric ulcers were mainly found in gastric antrum（440 sites,48.30%）,duodenal ulcers were mainly found in front wall of duodenum（3082 sistes 49.14%）,frost shape ulcer were mainly found in posterior duodenal bulb.（4）The majority of peptic ulcer diseases were found between the ages of 20 and 59 years（86.8%）.With age increasing,the tendency of duodenal ulcer was decreasing and compound ulcer was increased.（5）The number of ulcer sites found in winter was the biggest,the next was in spring,the third was in autumn,the fourth was in summer.Conclusion Duodenal ulcer is the most commom in female ulcers,duodenal ulcers is most commonly found in bulb.Frost shape ulcer is most commmonly found in posterior duodenal bulb.The majority of peptic ulcer diseases are found in youth and middle age people,peptic ulcer diseases in winter and spring were more than in autumn and summer.