营养干预对原发性肝癌介入治疗患者效果评价

Effect of Nutritional Intervention on Patients with Primary Hepatic Carcinoma Post Interventional Therapy

目的评价营养干预对原发性肝癌介入治疗患者的效果。方法回顾性分析2004年6月-2005年12月对在我院介入病区行初次或第2次介入治疗的48例原发性肝癌患者进行营养干预治疗的效果。结果将48例患者随机分为A、B两组，均进行营养指导，在介入治疗后饮食营养方案为A组常规饮食＋口服康全饮营养饮液200ml、每天2～3次，B组常规饮食。持续1月后，A、B组患者体重均增加，差异有统计学意义（P〈0．01），AB两组间体重变化值差异无统计学意义（P〉0．05）；A、B两组总蛋白（TP）增加，差异有统计学意义（A组P〈0．01、B组P〈0．05），AB两组间TP变化值差异有统计学意义（P〈0．05）；A组白蛋白（ALB）增加，差异有统计学意义（P〈0．01）、B组ALB增加差异无统计学意义（P〉0．05），AB两组间ALB变化值差异有统计学意义（P〈0：05）。结论营养干预治疗能改善原发性肝癌介入治疗患者的营养状况，有助进-步治疗。

Objective To evaluate the effect of nutritional intervention on the patients with primary hepatic carcinoma post interventional therapy. Methods The effect of nutritional intervention on 48 patients with primary hepatic carcinoma post 1st or 2nd interventional therapy in out＇hospital from June 2004 to December 200.5 was retrospectively analyzed. Re- suits Forty -eight patients were randomly divided into group A and group B, and all these patients were educated with nutri- tional knowledge. After interventional therapy, the nutritional treatment to group A was normal diet and oral nutritional agent 200ml per time, 2 or 3 times per day, while that to group B was just normal diet. After 1 month, the body weights （BW） of groups A and B patients all increased （ P 〈 0.01 ）, no statistically significant difference was found in the variation of body weight between the two groups （P 〉0.05）. TP of groups A and B patients increased, and the difference was statistically sig- nificant（group A： P〈 0.01, group B： P〈 0.05）. There were statistically significant differences in the variation value of TP between the two groups （P〈 0.05）. ALB of group A patients increased （P〈 0.0l ）, but ALB of group B patients did not in- crease （P 〉0.0.5）. And the variation value of ALB between groups A and B was different （P〈 0.05）. Conclusions Nutri- tional intervention can improve nutritional conditions of the patients with primary hepatic carcinoma post interventional therapy, it is helpful to the patients accept interventional therapy more.