复方丹参注射液治疗急性重度酒精中毒的疗效观察

Observation on efficacy of composite salvia miltiorrhiza injection in treating acute severe alcoholism

目的：观察复方丹参注射液治疗急性重度酒精中毒的疗效。方法：４５例急性重度酒精中毒患者随机分为２组。对照组２２例主要用纳络酮治疗；治疗组２３例在对照组治疗基础上，加用复方丹参注射液治疗，观察患者意识恢复及自觉症状改善、消失时间。结果：在取得起效、显效和痊愈时间上，治疗组分别为（３２．６±４．２）分钟，（５７．９±７．４）分钟和（１３２．２±１１．１）分钟，均明显早于对照组〔（５８．７±７．６）分钟，（８９．６±１０．３）分钟和（２０７．１±１５．３）分钟，Ｐ均＜０．０１〕；结论：复方丹参注射液与纳络酮合用治疗急性重度酒精中毒患者可缩短病程，提高疗效。

Objective:To observe the therapeutic efficacy of composite salvia miltiorrhiza injection on acute severe alcoholism(ASA).Methods:Fortyfive cases of ASA were divided randomly into 2 groups:control group ( n =22) was treated with naloxone and treatment group ( n =23) was treated with composite salvia miltiorrhiza injection on the basis of naloxone therapy.Then,to observe restorating consciousness time,improving and eliminating subjective symptoms time.Results:The initial improvement time,marked effective time and curative time were (32 6±4 2) minutes,(57 9±7 4)minutes and(132 2±11 1) minutes respectively in treatment group,they were shorten obviously than those in control group (58 7±7 6)minutes,(89 6±10 3)minutes and (207 1±15 3)minutes respectively,all P <0 01 .Conclusions:Composite salvia miltiorrhiza injection combined use of naloxone treating ASA can shorten disease course and enhance the therapeutic efficacy.