3Hiroaki y,Tani K,Kamegawa A,et al.Implications of the apuaporin-4 atructure on array formation and cell adhesion[J].J Mol Biol,2006,355(4):628 -639.
4Silberstein C,Bouley R,Huang Y,et al.Membrane organization and function of Mi and M23 isoforms of aquaporin-4 in epithelial cells[J].Am J Physiol Renal Physiol,2004,287(3):FS01 -FS11.
5Tait M J,Saadoun S,Bell BA,et al.Water movements in the brain:role of aquapofins[J].Trends Neurosci,2008,31(1):37 -43.
6Papadopoulos MC,Saadoun S,Binder DK,et al.Molecular mechanisms of brain tumor edema[J].Neuroscience,2004,129(4):1011-1020.
7Manley GT,Binder DK,Papedopoulos MC,et al.New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice[J].Neuroscience,2004,129(4):981 -989.
8Verkman AS,Binder DK,Bloch O,et al.Three distinct roles of aquaporin-4 in brain function revealed by knockout mice[J].Biochim Biophys Acta,2006,1758(8):1085-1093.
10Lee TS,Eid T,Mane S,et al.Aquaporin-4 is increased in the sclerotic hippocampus in human lemporal lobe epilepsy[J].Acta Neuropathol,2004,108(6):493-502.
2King LS, Agre P. Pathophysiology of the aquaporln water channels. Annu Rev Physiol,1996, 58 (2) :619-648.
3Jose L, Maria L, Alberto Machado, et al. Aquaporlns in the central nervous system. Prog Neurobiol, 2001,63(2) :321-336.
4Badaut J, Lasbennes F, Magistretti PJ, et al. Aquaporins in brain :distribution, physiology, and pathophysiology. J Cereb Blood Flow Metab, 2002 ,22 (4) :367-378.
5Aoki K, Uchihara T, Tsuchiya K, et al. Enhanced expression of aquaporin 4 in human brain with infarction. Acta Neuropathol (Berl), 2003,106(2) :121-124.
6Sun MC, Honey CR, Berk C, et al. Regulation of aquaporin-4 in a traumatic brain injury model in rats. J Neurosurg, 2003,98(3) :565-569.
7Briellmann RS, Wellard RM, Jackson GD. Seizure-associated abnormalities in epilepsy: evidence from MR imaging. Epilepsia,2005,46(5) :760-766.
8Kazuhiro Y, Naoki Y, Kiyofumi A , et al. Regulation of aquaporin-4 expression in astrocytes. Mol Brain Res, 2001,89 ( 1 ) : 94-102.
9Amiry-Moghaddam M, Otsuka T, Hum PD, et al. An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci USA, 2003,100(4) :2106-2111.
10Verkman AS. Aquaporin water channels and endothelial cell function. J Anat, 2002, 200(6) :617-627.
3Zhou HF,Liu XY,Niu DB,et al. Triptolide protects dopamin- ergic neurons from inflammation-mediated damage in duced by lipopolysaccharide intranigral injection [J]. Neu- robiol Dis,2005,18(3) : 441-449.
4Yool AJ. Aquaporins: multiple roles in the central ner- vous system [J]. Neuroscientist, 2007,13 (5) : 470-485.
5Binder DK,Oshio K,Ma T,et al. Increased seizure thresh- old in mice lacking aquaporin-4 water channels [J]. Neu-roreport, 2004,15 : 259-262.
6Lee TS,Eid T,Mane S,et al. Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe epilep- sy [J]. Acta Neuropathoi,2004,108(6) :493-502.
