D-二聚体检测在2型糖尿病并发症诊断中的应用

D-dimer in the detection of complications of diabetes diagnosis

目的研究血浆D-二聚体在2型糖尿病相关并发症诊断的价值。方法将74例糖尿病患者分为无并发症组(45例)、并发症组(29例),同时设健康对照组(46例),采用ELISA法分别测定各组血浆D-二聚体水平并进行比较。结果糖尿病并发症组D-二聚体水平明显高于健康对照组(P<0.001),其中无并发症组与健康对照组比较差异无统计学意义(P>0.05)。结论检测糖尿病D-二聚体是糖尿病并发血管病变的诊断指标之一。严格控制血糖、监测D-二聚体对防治糖尿病并发症有一定意义。

Objective To study the clinical significance of blood plasma D-dimer in diabetes mellitus patients. Methods Divides into 74 example diabetes group without the complication group （45 examples）, the complication group （29examples）,and carries on the comparison with the control group 46 examples, uses the ELISA method to determine each group of blood plasma D-dimer level separately. Results Diabetes complication group D-dimer level is higher than the control group obviously（P〈 0.01）. And does not have the complication group and the control group comparison difference does not have the significance （P〉0.05）. Conclusion The examination diabetes D-dimer is one of diabetes concurrent blood vessel pathological change＇s diagnosis targets. The strict control blood sugar, monitors the D-dimer to prevent and control diabetes complication to have certain significance.