醒脑静注射液对急性脑梗死患者血清超敏C-反应蛋白的影响及疗效观察

Impact of Xingniaojing Injection on Serum HS-CRP and Efficacy Observation in Acute Cerebral Infarction

目的探讨醒脑静注射液对急性脑梗死患者血清超敏C-反应蛋白(hs-CRP)水平的影响及临床疗效。方法将82例急性脑梗死患者随机分为对照组40例与治疗组42例,两组患者均同时口服肠溶阿司匹林片治疗,并根据基础疾病控制血糖、血压,对症支持治疗。在此基础上对照组患者应用生理盐水加丹参注射液治疗,治疗组患者应用生理盐水加醒脑静注射液。观察两组患者的临床疗效及hs-CRP水平情况。结果对照组总有效率为57.50%,治疗组为78.57%,两组比较有显著性差异(P<0.05)。治疗14 d后治疗组血清hs-CRP较治疗前降低(P<0.05),与对照组比较有显著性差异(P<0.05)。结论醒脑静注射液可有效降低脑梗死患者血清hs-CRP水平,改善神经功能,从而促进患者早期恢复。

Objective To explore the impact of xingnaojing injection on serum high sensitivity C - reactive protein（ hs -CRP）level and its clinical efficacy in the patients with acute cerebral infarction. Methods 82 cases of acute cerebral infarction were randomly divided into control group（40 cases）and treatment group（42 cases）. Aspirin enteric -coated tablet was administered orally in both groups and blood glucose and pressure were controlled and symptomatic supports were provided in accordance with basic diseases. On this basis, in control group, physiological saline and danshen injection were supplemented in treatment. In treatment group, physiological saline and xingnaojing injection were used. Clinical efficacy and hs - CRP level were observed in two groups. Results The total effective rate was 57.50% in control group and was 78. 57% in treatment group,indicating significant difference in comparison（P 〈 0.05 ）. 14 d after treatment,in treatment group, serum hs - CRP was reduced compared with that before treatment （ P 〈 0.05 ） , which was different significantly in comparison with the changes in control group（ P 〈 0.05 ）. Conclusion Xingnaojing injection reduces serum hs -CRP level effectively and improves nerve function in the patients with cerebral infarction so promote the early recovery of patients.