福州地区庚型肝炎病毒重叠感染

Superinfection of Hepatitis G Virus in Fuzhou

为研究庚型肝炎病毒在福州地区的重叠感染，采用ＥＬＩＳＡ法检测本院住院的２８６例病毒性肝炎（ＨＶ）患者和５００名供血员的抗－ＨＧＶ。结果表明，甲、乙、丙、戊型肝炎患者和供血员的抗－ＨＧＶ检出率分别为２．０％、２．２％、４．０％、１０．０％和０．２％。急性肝炎、慢性肝炎、慢性重型肝炎、肝硬化、原发性肝癌和抗－ＨＣＶ阳性供血员的检出率分别为７．９％、４．３％、３３．３％、０％、７．１％和６．３％，慢性重型肝炎检出率较慢性肝炎显著升高（Ｐ＜０．０５）。各型肝炎患者和供血员均存在庚型肝炎病毒重叠感染，以慢性重型肝炎为著。

To elucidate the characteristic of clinical epidemiology on hepatitis G virus(HGV)infection in Fuzhou.Anti-HGV in sera from 266 patients with virus hepatitis and 500 cases blood donors were detected by ELISA.Results.Showed that positivity rate of anti-HGV in 286 patients with hepatitis A、B、C、E and donors were 2.0%、2.2%、4.0%、10.0% and 0.2% respectively,and that of patients with virus heptitis significantly higher than donors,and that of donors with anti-HCV positive was more frequent than anti-HCV negative.One of infection of HGV was likely vertical transmission.Immunodeficiency might be another important pathogenic factor of HGV.The incidence of hepatitis B viral replication was found no lower in patients with superinfection of HGV than in those with HBV infection alone.The prolonged course of ALT was found to be longer in patient with superinfection of HGV than in those with virus infection alone.These results indicated that HGV infection in Fuzhou which had a district clinicoepidemiology characteristic.