经皮注射硬化剂治疗低流速型血管畸形

Percutaneous sclerosis therapy for low-flow vascular malformation

目的报告经皮注射硬化剂治疗低流速型血管畸形的疗效。方法23例浅表低流速型血管畸形患者进入研究。平阳霉素8mg、地塞米松5mg、2%利多卡因2ml、生理盐水2ml与少量对比剂混合后溶解配制硬化剂。DSA引导下经皮注射硬化剂,根据弥散情况及时终止注射。结果6个月至3年随访显示,血管畸形治愈率86.96%(20/23),好转率13.04%(3/23),总有效率100%。治疗后全部患者出现局部肿胀、疼痛,逐渐自行缓解;3例出现局部色素沉着;无发热、皮肤破溃、感觉异常、肺纤维化发生。结论经皮注射硬化剂治疗低流速型血管畸形安全、有效。

Objective To report experience of percutaneous sclerosis therapy for low-flow vascular malformation. Methods Twenty-three patients with superficial vascular malformation of low-flow pattern were enrolled in this study. Little amount of contrast medium, 8 mg Pingyangmycin, 5 mg Dexamethasone, 2 ml 2% Lidocaine and 2 ml sodium chloride were mixed as sclerosing agent. Sclerosing agent was injected under DSA. Results Six to 36 months follow-up revealed that cu- ring rate was 86.96%（20/23）, improvement rate was 13.04% （3/23）, overall effective rate was 100%. Local swelling and pain present on all of subjects and disappeared gradually without treatment. Local sedimentation occured in 3 cases. No fever, skin ulceration, abnormal sensation or lung fibrosis were observed. Conclusion Percutaneous sclerosis therapy for low-flow vascular malformation is safe and effective.