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内皮素、组织因子及D-二聚体对急性胰腺炎严重程度的早期判断价值 被引量:3

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摘要 目的探讨内皮素(ET)、组织因子(TF)和D-二聚体(D-D)对急性胰腺炎(AP)严重程度的早期判断价值。方法收集经临床确诊发病24h内的33例AP患者,其中重症AP14例(SAP组)和轻症AP19例(MAP组),另选择10例健康体检者作为对照组(CG组),分别测定ET、TF、D-D水平,并进行比较。结果SAP组ET、TF和D.D水平[(129.95±35.97)ng/L、(98.40±57.33)ng/L、(885.50±360.64)μg/L]与MAP组[(56.91±15.81)ng/L、(7.63±5.81)ng/L、(275.97±173.71)μg/L]及CG组[(13.59±4.89)ng/L、(4.25±2.35).g/L、(180.10±80.54)μg/L]比较差异均有统计学意义(P〈0.01);TF、D-D在MAP组与CG组之间差异无统计学意义(P〉0.05),而ET在MAP组与CG组之间差异有统计学意义(P〈0.05);在AP患者中,ET与TF呈正相关(r=0.617,P〈0.01),ET与D-D呈正相关(r=0.619,P〈0.01),TF与D-D亦呈正相关(r=0.635,P〈0.01)。结论ET、TF和D-D对AP病情严重程度有早期判断价值。
出处 《中国医师进修杂志(内科版)》 2009年第6期48-50,共3页 Chinese Journal of Postgraduates of Medicine
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