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布地奈德与地塞米松灌肠治疗溃疡性结肠炎临床观察 被引量:2

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摘要 目的了解布地奈德与地塞米松灌肠治疗溃疡性结肠炎的疗效及不良反应。方法选择32例溃疡性结肠炎患者随机分为两组,布地奈德组12例给予布地奈德2mg加0.9%NaCl溶液100ml稀释混合;地塞米松组20例给予地塞米松10mg加0.9%NaCl溶液100ml混合摇匀,均加热至35~37℃,睡前保留灌肠,每晚1次,疗程2周。治疗后复查肠镜观察疗效及不良反应。结果布地奈德组显效8例,有效4例,总有效率100.0%;地塞米松组显效10例,有效8例,无效2例,总有效率90.0%,两组总有效率比较差异无统计学意义(P〉0.05)。布地奈德组有1例出现肛周不适。地塞米松组有4例出现轻微不良反应。结论布地奈德与地塞米松灌肠治疗溃疡性结肠炎疗效相当,前者不良反应小。
出处 《中国医师进修杂志(内科版)》 2009年第6期58-59,共2页 Chinese Journal of Postgraduates of Medicine
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