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二膦酸盐类药物治疗骨质疏松症的研究进展 被引量:4

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摘要 二膦酸盐类(bisphosphonates,BPs)药物治疗骨质疏松症的机制 BPs药物是焦磷酸盐类似物,含1个磷酸盐-碳-磷酸盐(P—C—P)核心结构,该结构使其能靶向作用于骨骼并抵抗酶分解作用。将复合物侧链连接到P—C—P核心,特别是将氮原子引入到一个烷基链,从而生成抗吸收能力增强的复合物。
出处 《中国骨与关节外科》 2009年第2期131-135,共5页 Chinese Journal of Bone and Joint Surgery
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