广东省斗门县老年性黄斑变性流行病学调查

The prevalence of age related macular degeneration in Doumen County,Guangdong Province

目的了解广东省斗门县５０岁以上人群中，老年性黄斑变性（ａｇｅ－ｒｅｌａｔｅｄｍａｃｕｌａｒｄｅｇｅｎｅｒａ－ｔｉｏｎ，ＡＭＤ）的患病率。方法随机整群抽样后，根据户口登记本进行严格的检录登记，用ＥＴＤＲＳ视力表查视力，并完成包括外眼、角膜、晶体和眼底等检查。根据全国眼底病学组制订的ＡＭＤ的诊断标准，同时参考弗拉明汉（Ｆｒａｍｉｎｇｈａｍ）研究关于ＡＭＤ的视力要求作出诊断。结果实际受检者５３４２人，受检率占９２．８％，ＡＭＤ总检出率８．４％。在５０～５９、６０～６９、７０岁以上３个年龄组ＡＭＤ的检出率分别为２．９％、７．８％和１２．９％。受检者中男性检出率为８．５％，女性为８．４％。ＡＭＤ的患眼中，５％是盲眼，４９％为低视力眼。结论ＡＭＤ患病率高，视功能损害严重。患病率随年龄增加显著增加。

Purpose To describe the prevalence of age related macular degeneration (AMD)in the population aged 50 and over in Doumen County of Guangdong Province. Methods After randomized clustering sampling,all selected individuals were enumerated according to village residence register.Visual acuity were measured by illuminated EDTRS chart.The examination of eyelid,cornea,lens and fundus were also carried out.The diagnosis of AMD was made according to the criteria of National Academic Group of Fundus Diseases combining with the visual criteria of Framingham Eye Study. Results 5 342 individuals were examined with participating rate of 92.8%.The overall prevalence of AMD was 8.4%.The prevalence of 2.9%, 7.8%and 12.9%was found in the age groups of 50～,60～,70～ respectively.The prevalence of male and female was 8.5%and 8.4%respctively.5%of AMD eyes were blind and 49%were low vision. Conclusion The prevalence of AMD is high and increased with aging,but not correlated with sex.AMD can cause severe visual impairment.