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中西医结合治疗类风湿关节炎活动期的安全性观察 被引量:1

A clinical research of safety on treatment of active rheumatoid arthritis with integrated traditional and westen medicine
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摘要 目的:研究祛风除湿、活血养阴中药治疗类风湿关节炎活动期的安全性影响。方法:90例活动期类风湿关节炎病例按性别、年龄、病程均衡后分为基础治疗组、激素组及中药组各30例,分别采用非类固醇抗炎药+改变病情药、小剂量泼尼松+非类固醇抗炎药+改变病情药、中药+非类固醇抗炎药+改变病情药疗8周,评价各组安全性。结果:不良反应的累计积分3组中药组(4.33±2.41)<基础治疗组(8.97±5.12)<激素组(12.67±7.19),3组组间比较差异有统计学意义(P<0.05),结论:中西医结合治疗类风湿关节炎活动期具有更好的安全性。 To study the safety of expel wind-evil and remove wetness, promoting blood flow, invigorating yin Chinese herb in treating active rheumatoid arthritis (RA) . Methods 90 patients with active rheumatoid arthritis were randomly allocated to 3 groups: Single NSAID, DMARD×8 weeks (Basic treatment group) , prednisone in combination with NSAID, DMARD×8 weeks (GC group) or Chinese herb in combination with NSAID, DMARDsx8 weeks (Chinese herb group) . Adverse effects of every group were analyzed respectively. Result Adverse effects score was significantly different among the 3 groups. Conclusions Treatment of active rheumatoid arthritis with integrated traditional and westen medicine was the safest among the 3 groups.
出处 《中国民族民间医药》 2009年第9期40-41,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词 关节炎 类风湿 中药 安全性 Arthritis, rheumatoid Chinese herb safety
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  • 1Fries JF,Spitz PW,Williams CA,et al.A toxicity index for comparison of side effects among different drugs[].Arthritis and Rheumatism.1990
  • 2American College of Rheumatology and HOC Committee of Clinical Guidelines.Guideline for monitoring drug therapy in rheumatoid arthritis[].Arthritis and Rheumatism.1996
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  • 5American College of Rheumatology and HOC Committee of Clinical Guidelines.Guideline for the management of rheumatoid arthritis[].Arthritis and Rheumatism.1996

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