1990-2007年山东省乙型肝炎发病趋势分析

Epidemiological Trend of Hepatitis B in Shandong Province of China,1990-2007

目的分析山东省1990-2007年乙型肝炎发病的流行趋势,发现重点人群,进一步探讨防治策略。方法根据历年乙肝报告的发病资料和人口资料,计算历年发病率以及性别、年龄别发病率,并建立简单线性回归模型进行统计分析。结果1990-2007年山东省共报告乙肝发病437 094例,年均发病率27.32/10万,男性发病率(38.42/10万)高于女性(15.83/10万);总体发病率呈上升趋势,但0～9岁年龄组呈显著下降趋势;平均发病年龄呈后移趋势。结论男性青壮年为乙肝发病的重点人群,预防乙肝应在提高对新生儿乙肝疫苗接种率的基础上,加强对其他人群尤其是高危人群的接种工作。

Objective To analyze the epidemiological trend of hepatitis B from 1990 to 2007 in Shandong province, and to find the high risk population so as to explore the further control strategy. Methods Based on the routine reporting incidence data of hepatitis B and demographic data of Shandong province, the incidence rates and sex - specific, age - specific incidence rates of hepatitis B were calculated and statistically analyzed in the simple linear regression model. Results The total numder of hepatitis B was 437 094, the annual average morbidity was 27.32 per 100 000 population during 1990 to 2007. The incidence of men （38.42 per 100 000）was higher than that for women （ 15.83 per 100 1300）. The annual incidence rate of hepatitis B indicated an increasing trend for the whole population, while a decreased trend for the 0 - 9 year - old children presented in the past 18 years. It showed that the average age of onset moved to the older. Conclusion Young adult men are the focus groups for the onset of hepatitis B. For the prevention of hepatitis B, the immunization of hepatitis B vaccine should be enhanced for other groups, especially for the high - risk population on the basis of improving the immunization coverage rate for newborns.