375例妊娠晚期孕妇凝血4项测定的临床价值

Discussion of Clinical Application Value to Detecting the Function of Blood Coagulation for Late-pregnant Women

目的探讨检测妊娠晚期孕妇血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)的临床应用价值。方法对375例晚期孕妇组(实验组)与133例健康非妊娠妇女组(对照组)的凝血4项指标进行比较分析。结果晚期孕妇组PT、APTT、TT较对照组明显缩短(P<0.01)、FIB明显增多(P<0.01)。结论妊娠晚期孕妇处于高凝状态,及时监测凝血4项指标对预测、治疗产妇异常出血有临床应用价值。

Objective To explore the clinical Application Value of detecting prothrombin time（PT） ,the activated partial thromboplasting time（APTT）, thrombin time （TT）, plasma fibrinogen （FIB） for late-pregnant women. Methods The results of PT, APTT, TT, FIB for 375 late-pregnant women（experiment group） and 133 normal women without pregnant（control group） were compared. Results As compared with that of control--group, PT, APTT and TT in late-pregnant women group were decreased significantly （P〈0.01） while FIB was more elevated （P〈0.01）. Conclusion The late-pregnant women are in a hypercoagulation state,which has Clinical value to detect the function of blood coagulation for late-pregnant women, especially when late-pregnant women show abnormal bleeding.