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黄酮类化合物对前列腺癌的防治作用

Preventive and Therapeutic Effects of Flavonoids on Prostate Carcinoma
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摘要 黄酮类化合物是一类存在于多种植物中的多酚化合物,能够促进健康、预防疾病,并用于预防癌症。它们具有安全低毒的特点,是良好的化疗药物。其对癌症的保护机制主要表现在抗细胞增殖、诱导细胞凋亡、干预细胞信号转导和增强抑癌基因活性及抑制癌基因表达等方面。就黄酮类化合物对前列腺癌预防和治疗的研究进展进行综述。 Flavonoids are series of polyphenol compounds in many kinds of fruits, vegetables and beverages. Flavonoids are described as health-promoting, disease-preventing dietary supplements and have activities as cancer preventive agents. Additionally, they are extremely safe and associated with low toxicity, which make them excellent candidates for chemopreventive agents. The anticancer effects of flavonoids display as anti-proliferation, including apoptosis, modulating signal transduction, enhancing activities of anti-oncogenes and inhibiting expression of oncogens. This review focuses on the research of prevention and treatment of flavonoids in prostate carcinoma.
作者 孙怡
机构地区 南京中医药大学基础医学院
出处 《辽宁中医药大学学报》 CAS 2009年第6期48-50,共3页 Journal of Liaoning University of Traditional Chinese Medicine
基金 中国博士后科学基金资助项目(2005037217)
关键词 黄酮类化合物 前列腺癌 综述 flavonoid prostate carcinoma review
分类号 R730 [医药卫生—肿瘤]
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  • 1Kyprianou N, King E D, Bradbury D, et al. Bcl-2 overexpreasion delays radiation-induced apoptosis without affecting the clonogonic surrival of human prostate cancer cells. Int J Cancer, 1997, 70(3) :341.
  • 2Sun X M, MacFarlane M, Zhuang J, et al. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem, 1999, 274(8) :5 053.
  • 3Guo Y, Kyprianou N. Restoration of transforming growth factor-β signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis. Cancer Res, 1999,59(6):1 366.
  • 4Taille A de la, Chert M W, Shabsigh A, et al. Fas antigen/CD-95 upregulation and activation during castration-induced wgression of the rat ventral prostate gland. Prostate, 1999, 40(2):89.
  • 5Bowen C, Voeller H J, Kikly K, et al. Synthesis of pro-caspaae-3 and-7 during apoptosis in prostate cancer. Cell Death Differ, 1999,6(5) :394.
  • 6Day M L, Zhao X, Vallorosi C J, et al. E-cadherin mediates aggregation-dependent survival of prostate and mammary epithelial cells through the retinoblastoma cell cycle control pathway. J Biol Chem,1999, 274(14) :9 656.
  • 7Kyprianou N, King E D, Bradbury D, et al. Bcl-2 overexpression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells. Int J Cancer, 1997, 70(3) :341.
  • 8Sun X M, MacFarlane M, ZhuangJ, etal. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem, 1999, 274(8):5 053.
  • 9Taille A de la, Chen M W, Shabsigh A, et al. Fas antigen/GD-95 upregulation and activation during castration-induced regression of the rat ventral prostate gland. Prostate, 1999, 40(2):89.
  • 10Bowen G, VoellerHJ, Kikly K, etal. Synthesis ofpro-caspase-3 and -7 during apoptosis in prostate cancer cells. Cell Death Differ, 1999,6(5) :394.

共引文献35

辽宁中医药大学学报
2009年 第6期

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