Child-Pugh分级对失代偿期肝硬化预后的评估

Child-Pugh's Score in Prediction of Prognosis of Patients with Decompensated Liver Cirrhosis

目的:研究Child-Pugh分级对失代偿期肝硬化预后的预测价值。方法:对34例死于失代偿期肝硬化患者进行回顾性分析,应用Child-Pugh分级对初次入院资料进行评分及分级,并计算初次入院至死亡的时间。结果:Child-Pugh分级A级生存时间56.2±24.7月、B级33.1±10.5月、C级12.6±9.6月;以上消化道出血为主要表现的患者,生存时间相对非出血者低(P<0.05)。结论:Child-Pugh分级可做为预测失代偿期肝硬化患者的生存时间的重要的客观指标。而是否伴有上消化道出血对生存时间有较大的影响;上腹部增强CT对失代偿期肝硬化患者有无肝肾分流等侧支循环的评估有助于出血风险的判断。

Objective： To evaluate the prognosis of patients with decompensated liver cirrhosis by Child-Pugh＇ s score. Methods： Thirty-four patients died of decompensated liver cirrhosis were graded with Child-Pugh according to the clinic data of the first admission and the survival time was calculated. Results： The survival time of Child-Pugh＇s score A was 56.2±24.7months, Child B was 33.1±10.5months, Child C was 12.6±9.6months. The survival time of the patients with manifestation of upper gastrointestinal bleeding was shorter than those without bleeding（P〈0. 05）. Conclusion： Child-Pugh＇s score can accurately predict the prognosis of patients with decompensated live cirrhosis, but the upper gastrointestinal bleeding should be taken into account and CT is helpful to predict bleeding.