高龄人白内障术前的角膜内皮细胞及厚度的检查

The Examination of Corneal Endothelial Cells and Center Corneal Thickness in the Senile Patients before Cataract Surgery

目的:探讨高龄白内障患者术前角膜内皮功能状态。方法:对从2007年11月到2008年10月的66例年龄在80岁或以上的左眼白内障患者术前角膜内皮细胞形态及中央角膜厚度进行回顾性分析。分析参数包括角膜内皮细胞密度,内皮细胞平均面积,最大细胞面积和最小细胞面积,内皮细胞变异系数,面积标准差,六角形细胞比例及角膜中央厚度。结果:患者的角膜内皮细胞平均密度为(2720.3±324.6)个/mm2,平均细胞面积为(375.4±70.3)μm2,最大细胞面积(922.1±243.5)μm2,最小细胞面积(131.2±40.2)μm2,面积标准差(143.5±34.8)μm2,细胞变异系数(38.0±7.3)%,六角形细胞比例(52.8±10.1)%。中央角膜厚度与角膜内皮细胞密度之间无相关性。结论:高龄人白内障患者的角膜内皮细胞密度高,角膜功能基本正常,是保持角膜透明的基础,为眼内手术或治疗提供安全保障。

Objective： To explore the function and morphology of corneal endothelial cells in the senile patients needing cataract surgery. Methods： The data collected from 66 left eyes of the senile patients （at least 80 years old） were retrospectively analyzed by using non-contact automatic specular microscope （TOPCON SP3000P）. The following parameters were included： the density and size of endothelial cells, the percentage of hexagonal cells and the central corneal thickness, u-test was used in this study. Results： The average density of endothelial cells was （2720.3±324.6）/mm^2 , the average cell size （375.4±70.3）μm^2 , ranging from a maximum size of （922.1±243.5）μm^2 to a minimum size of （131.2±40.2） μm2. The standard deviation of the average cell size was （143.5±34.8） μm^2 and variation 38.0±7.3%. The ratio of hexagonal cells was 52.8±10.1%. There was no correlation between central corneal thickness and the density of corneal endothelial cells. Conclusion： The endothelial cell density is high in the senil cataract patients, which indicates that the corneal function of the senile patients is normal. The high density main tains the corneal transparency and will facilitate surgery.