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雄激素受体与P21活化激酶在前列腺癌发生中的作用

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摘要 前列腺癌为老年病，是欧美国家最常见的肿瘤，随着人类平均寿命的延长和诊断技术的提高嘞列腺癌在世界癌症总发病数中占十分之一，伞球范围内每年约有20万患者死于前列腺癌。在美国，前列腺癌已经跃居第2位致死癌，约半数年龄大于50岁男性前列腺中可发现癌细胞。前列腺癌的发病原因迄今仍不清楚，目前认为激素、人种、遗传和饮食习惯等与发病都有比较密切的关系，其中雄激素在前列腺（癌）的生长、转移与分化中起决定性作用，由雄激素依赖性转变为雄激素非依赖性是每个致死性前列腺癌细胞的根本特性。
作者 王新敏 丁国富
机构地区 石河子大学医学院 石河子大学医学院第一附属医院泌尿外科
出处 《农垦医学》 2009年第2期163-165,共3页 Journal of Nongken Medicine
关键词 前列腺癌细胞 雄激素受体 癌发生 P21 雄激素非依赖性 激酶 活化 人类平均寿命
分类号 R737.25 [医药卫生—肿瘤] R730.231 [医药卫生—肿瘤]
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参考文献21

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二级参考文献11

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农垦医学
2009年 第2期

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