253例孕妇血中微量元素水平分析

Analysis on the levels of trace elements in serum of pregnant women

目的:探讨253例孕妇不同孕期血液中铁,锌,锰,铜,硒5种微量元素变化水平。方法:按孕周将253例孕妇分为早、中、晚孕3组。47例健康未孕育龄妇女为对照组,采用原子吸收光谱仪进行测定。结果:随着孕周增加,孕妇血中锌和硒明显降低;铜明显升高;锰早孕期稍降,中、晚孕期升高;铁早孕期升高,中、晚孕期降低。孕妇不同孕期血中铜、锌和硒与对照组差异均有统计学意义(P<0.05);铁在早孕期、晚孕期与对照组差异均有统计学意义(P<0.05);锰只有晚孕期与对照组差异有统计学意义(P<0.05)。结论:孕妇不同孕期血液中铁,锌,锰,铜,硒5种微量元素变化水平存在地区差异,因此应建立该地区的参考值。

Objective： To explore the changes of trace elements （iron, zinc, manganese, cuprum and selenium） levels in serum from 253 pregnant women in different pregnant stages. Methods： 253 pregnant women were divided into three groups according to pregnant weeks ： the early pregnant group, the middle pregnant group and the late pregnant group. 47 non - pregnant women were selected as control group. The levels of trace elements in serum of two groups were detected by atomic absorption spectrophotometry （AAS） . Results： The levels of zinc and selenium decreased with the increasing of pregnant weeks, while the level of cuprum increased. The level of manganese decreased in early pregnant stage, then went up in middle and late pregnant stage, while the level of iron reversed. There was significant difference in the levels of cuprum, zinc and selenium between two groups in different pregnant stages （ P 〈 0. 05 ） . There was significant difference in the level of iron between two groups in early and late pregnant stages （ P 〈 0. 05 ） . There was significant difference in the level of manganese between two groups in late pregnant stage （ P 〈 0. 05） . Conclusion： To establish the reference values of trace elements of pregnant women in Zhongshan is very important.