摘要
研究了睡莲科芡属植物芡(Euryale Ferox Salisb.)的成熟种仁芡实的环肽成分.芡实药材经95%甲醇回流提取后,通过硅胶,Pharm adex LH-20凝胶,RP-18反相柱层析进行分离,从中分离鉴定了3个环二肽.其结构经化合物的理化性质测定和光谱数据分析分别鉴定为:环(苯丙-丝)(1),环(丙-脯)(2),环(苯丙-丙)(3),其中化合物1为新的天然产物,化合物2和3为首次从该植物中分离得到.
To investigate the Cyclic peptides in the seeds of Euryale ferox Salisb for obtaining a more comprehensive understanding on its effective components. Three cyclic peptides were obtained by column chromatography with silica gel, Pharmadex LH -20 and reversed-phase silica gel. Their structures were elucidated by spectral analysis and chemical evidence as Cyclo（ Phe - Ser） （ 1 ）, Cyclo （Ala -Pro） （2）, Cyclo（ Phe -Ala） （3）. And compound 1 was a new natural compound; compounds 2 and 3 were isolated from this plant for the first time.
出处
《昆明学院学报》
2009年第3期39-41,共3页
Journal of Kunming University
基金
云南省自然科学基金资助项目(2007B021M)
关键词
芡实
环二肽
分离
Euryale ferox Salisb
Cyclic peptide
isolated
