中西医治疗非酒精性脂肪性肝炎研究述略

Non -alcoholic Steatohepatitis Study of Chinese and Western Medicine

[目的]对非酒精性脂肪性肝炎的中西医研究进展进行总结归纳，以期找到目前研究的空白点，为今后的继续探索提供线索。[方法]检索近10年的文献，从发病机理、西医治疗方法、中医治疗概况及其他研究等几个方面进行概括总结。[结果]西医尚无专门针对NASH治疗的特效药物，中医治疗NASH的用药证型局限，针对痰、湿、瘀等治标药物较多，而对于先天肾的药物偏少，在治则治法上缺乏突破和创新。绝大部分医生方剂的创立是经验的，自发的，个体性的，具有经验局部性，时间短暂性，病源地域性等诸多限制，效率低下，经验的总结和继承花费的时间漫长，而循证医学已经成了NASH研究的热点，并且成为了临床实践的新范例、新模式。[结论]根据临床需要采用更加适合的治法治则，并且在此基础上创立新的方剂成为了目前研究的趋势，因此迫切需要一种高效率的经验分析及拟方方法。

[ Objective]To find the blank and give the direction in the future by studing the research progression of nonalcoholic fatty liver disease by western and traditional Chinese medicine. [Method] By reviewing the articles within 10 years, to summarize experiences from the aspects of pathogenesis, therapy of western and traditional Chinese medicine and other treatments. [ Result ] There are no specific western medicines to cure NASH, the types of syndrome are limited in TCM, the drugs towards sputum, moist, congestion are more than those of kidney, so it is lacking of creativeness. Prescriptions of most TCM doctors are empirical, spontaneous and individual. So their experiences are limited, transient, local and inefficient, and it＇ s too long to inherit their experiences. Evidence -basedmedicine is the hot spot of NASH ,and becoming the new model,new pattern of clinical practices. [ Conclusion ] It＇ s a trend to adopt more suitable therapeutic principles and new prescriptions, so it urgently needs a analysis methods with high efficiency.