强直性脊柱炎合并肾脏损害的临床分析

目的分析强直性脊柱炎（AS）患者合并肾脏损害的临床特点。方法回顾性分析近年来本院收治的AS患者的病例资料，分析其临床表现、实验室检查（包括尿常规、24h尿蛋白定量、肾功能、HLA—B27、ANA、ANCA等）、肾脏B超、肾脏病理等。结果AS与肾脏损害存在相关性，其机制未明，临床表现可不明显，易被忽视，临床应引起重视，特别是对仅有轻度尿检异常的AS患者应积极随访观察，必要时行肾脏病理检查。

Objective To study the clinical character of ankylosing spondylitis combined with renal impairment. Method Of the clinical data of the hospitalized ankylosing spondylitis （ AS ） patients in recent years were retrospectively investigationcarried, including clinical findings, routine examination of urine, 24h urinaryprotein, renal function, HLA - B27, ANA, ANCA, renal B - ultrasonic and renal pathology. Results There were a correlation between AS and renal impairment, the mechanism is not clear. The clinical findings were sometimes not evident. Conclusion More attention and follow up should be give to the AS patients with even slight abnormality in urine test based on the fact that AS is correlated with renal impairment, a renal biopsy can be carried out also when necessary.