百参口服液抗衰老的实验研究

Anti-aging effect of Baishen oral liquid : An experimental study

目的:观察百参口服液抗衰老作用。方法:将雌雄各半的50只KM小鼠随机分为5组:空白对照组、模型组、高、中、低剂量给药组,每组10只。空白对照组皮下注射生理盐水,5g.mL-1,1次/天,衰老模型组皮下注射D-半乳糖(5g.k-g 1),1次/天,各给药组在D-半乳糖致衰老的基础上,不同剂量连续给药42d后,处死,采血,分离血清并测定生化指标。结果:百参口服液能使小鼠血清GSH-Px活性明显上升。结论:百参口服液可延缓小鼠衰老,提高抗氧化能力。

Objective：To observe the anti--aging effect of Baishen oral liquid. Method：50 male and female mice geban KM were randomly divided into 5 groups： control group,aging model and low, middle and high dosage groups of Baishen oral liquid with 10 mice in each. The control mice were injected subcutaneously with 5mL·kg^-1 saline once daily,and the mice of the aging model group,with 5g·kg^-1 D--galactose once daily, and the mice of low, middle and high dosage groups of Baishen oral liquid,after their aging models were induced with D--galactose, were given low,middle and high dosages,respectively for 42 days,then killed and serum was separated for the determination of biochemical parameters. Result：Baishen oral liquid could increase the activity of serum SOD. Conclusion ： Baishen oral liquid has some effects on aging delay, and has obviously antioxidation.