摘要
葡萄糖是多数哺乳动物的主要能量来源,必须保持它的正常转运和代谢。葡萄糖在细胞内外的转运主要依靠葡萄糖转运蛋白（GLUTs）。GLUTs广泛地分布在人体各组织当中,对于维持组织的正常生理功能起到了重要的作用。组织不同,分布的GLUTs的类型也不相同。糖尿病患者异常的高水平葡萄糖导致GLUTs mRNA和蛋白表达的改变,这可能在糖尿病慢性并发症的发病机制中起到了重要的作用。
Glucose is a major source of energy for most mammalian cells, and it is necessary for cells to maintain glucose levels in normal transport and metabolism. Glucose Transportes（GLUTS） are the main cellular transporters that mediates the uptake of glucose. GLUTS are distributed extensively over all tissues of the body and are needed in keeping tissues in normal physiological function. There are different types of GLUTS in different tissue. And the abnormally high level of glucose, as seen in diabetes,leads to the changed expression of GLUTS mRNA and protein, which may play an important role in the mechanism of diabetes-related diseases.
出处
《医学综述》
2009年第11期1687-1689,共3页
Medical Recapitulate
基金
广东省自然科学基金(8451018201001067)
