冠心宁注射液对老年肺心病并发冠心病患者QT离散度的影响

Effect of Guanxinning Injection on the QT Dispersion in Old Patients with Pneumocardial Disease Complicated with Coronary Artery Disease

目的探讨冠心宁注射液对老年肺心病并发冠心病患者QT离散度的影响。方法将106例老年肺心病并发冠心病患者随机分为两组,各53例。对照组采用常规治疗;治疗组在常规治疗基础上加用冠心宁注射液20 mL静脉滴注,qd,共14 d。结果治疗组治疗前后QT离散度分别为(78.70±19.72)及(48.30±20.63)m s,差异有极显著性(P<0.01);对照组QT离散度治疗前后差异无显著性(P>0.05)。结论冠心宁注射液可降低老年肺心病并发冠心病患者QT离散度。

Objective To explore the effect of guanxinning injection on the QT dispersion in old patients with pneumocardial disease complicated with coronary artery disease. Methods 106 old eligible patients were divided into two groups. The control group was （53 cases） given with regular treatments. The test group （53 cases） was intravenously infused with 20 mL of guanxinning injection per day for 14 days, in addition to regular treatments. The changes of QT dispersion were observed in two groups. Results Signifciant changes of the QT dispersion after treatment were found in the test group [ （78.70 ± 19.72） ms versus （48.30±20.63） ms, P 〈0.01 ] , while, no significant changes were observed in the control group （P 〉 0.05）. Conclusion Guanxinning injection can reduce the QT dispersion in pneumocardial disease complicated with coronary artery disease.