胃食管反流诊断技术进展

Progress of Diagnostic Techniques for Gastroesophageal Reflux

胃食管反流病（GERD）的患病率逐年上升。诊断GERD的手段较多，如典型症状（胃灼热和反酸）、质子泵抑制剂试验、X线钡餐、食管放射性核素检查、上消化道内镜、24h食管pH监测等。但是，许多患者并没有明显的酸反流和症状之间的关系的证据，非糜烂性和质子泵抑制剂抵抗的GERD也逐渐被认识。本文就近几年来GERD检测技术进展予以综述。

The prevalence of gastrnesophageal reflux disease （GERD） tends to be increased in China. There are various approaches to diagnosis GERD, including heartburn and acid regurgitation, proton pump inhibitor test, the barium meal, esophageal radionuclide studies, upper gastrointestinal endoscopy and 24 hour ambulatory pH monitoring. In many patients, however, there is a poor correlation between acid reflux episodes and symptoms. The patients with nonerosive gastroesophageal reflux disease and the patients with GERD refractory to adequate proton pump inhibitor therapy are now recognized. Efforts have been made to detect all types of gastroesophageal reflux and to increase the likelihood of documenting the relationship between symptoms and reflux events by prolonging the recording periods.