早期梅毒四种检测方法比较

Comparison of Four Testing Methods of Early Syphilis

目的：比较早期梅毒四种检测方法。方法：收集临床诊断为Ⅰ期梅毒的临床标本40例（同时取溃疡面渗出液及血液标本），分剐用暗视野显微镜检测、甲苯胺红不加热血清试验（TRUST）、梅毒螺旋体血凝试验（TPHA）及聚合酶链反应（PCR）四种方法同时进行检测，并对结果作对比分析。结果：四种检测方法的阳性率分别为：暗视野显微镜；TRUST；TPHA;PCR。后者与前三种方法比较阳性率有显著性差异（P〈0．05）。结论：PCR技术在Ⅰ期梅毒检测中具有较高的灵敏性，对梅毒的及时发现和治疗具有重要意义。

Objective： To compare the four testing methods of early syphilis. Methods： Collecting 40 cases of clinical simples that were diagnosed as early syphilis and testing them with microscopic test, TRUST, TPHA and PCR. Results： The positive rate of PCR has significant difference with the rest three methods. Conclusion： PCR technology has high sensitivity in testing early syphilis.