麻仁软胶囊改善功能性便秘患者肠道动力障碍的临床研究

Maren Soft Capsule improves functional constipation patients with gastrointestinal motility disorder

目的观察麻仁软胶囊治疗功能性便秘患者肠道动力障碍的临床疗效及对患者结肠传输功能的影响。方法将90例功能性便秘的患者完全随机分为2组，治疗组60例患者采用麻仁软胶囊治疗，对照组30例患者给予麻仁丸治疗，2组均治疗14d，治疗前后均进行结肠传输试验检查，观察症状的改善情况及便秘类型的分布情况，以及标记物的结肠通过时间变化。结果麻仁软胶囊治疗组总有效率为63．33％，对照组总有效率46．67％，2组比较差异有统计学意义（P〈0．05）；治疗组粪便性状和腹胀主症的改善程度明显优于对照组（P〈0．01）；治疗组治疗后分段结肠通过时间分别为：（8．21．±1．66）h（右半结肠）；（17．35±7．75）h（左半结肠）；（30．73±7．12）h（直乙状结肠），与对照组治疗后3段时间（9．91±2．85）h、（19．55±6．49）h、（33．84±8．21）h比较，差异有统计学意义（均P〈0．01）。结论麻仁软胶囊能够改善功能性便秘患者肠道动力障碍，能够软化粪便并促进结肠蠕动，临床疗效满意。

Objective To investigate the effect of Maren Soft Capsule on functional constipation with gastrointestinal motility disorder. Methods Ninty patients were included in the study. 60 cases in the trial group were treated with Maren soft capsule and 30 cases were treated with March Wan for two weeks. Improvement of the gastrointestinal motility disorder and tcm symptoms before and after treat were analyzed. Results The total effective rate was 63.33% with significant improvement in fecal character and the tcm symptoms. （P 〈0.01 ）. Conclusion March Soft Capsule improves functional constipation with gastrointestinal motility disorder.