摘要
目的:探讨腹腔灌注化疗联合局部高频热疗治疗恶性腹水的疗效。方法:将符合条件的患者随机分成治疗组(N=21)和对照组(N=19)。化疗方案采用生理盐水500ml+顺铂60mg/m2、速尿20mg快速灌注入腹腔,每周灌注1次,连续灌注2周。治疗组化疗同时给予局部高频热疗2次/周、60分钟/次。对比两组治疗效果。结果:治疗组有效率(66.7%)高于对照组有效率(42.1%)(P<0.05),生活质量改善治疗组高于对照组,有显著性差异。结论:对于恶性腹水患者,采用腹腔灌注化疗联合局部高频热疗可获得较好的临床疗效。
Objective:To investigate the effects of chemotherapeutic intraperitoneal perfusion combined with local high freguency hyperthermia for the treatment of malignant ascites. Methods:Forty cases of malignant aseites were randomly divided into treatment group (N = 21 ) and control group (N = 19). Chemotheraputie project as follows: physiological saline (500ml) + eisplatin (60mg/m2) + furosemide (20mg) were infused into abdominal cavity rapidly (once a week, continuation for two weeks). In the treatment group, the patients were treated with local high freguency hyperthermia (60 min, twice a week). Therapeutic effect of the two groups was evaluated. Results: The response rate in treatment group (66.7%) was significantly higher than in the control group (42. 1% ) (P 〈 0.05 ), Quality of life in treatment group was significantly higher than in the control group ( P 〈 0.05 ). Conclusion: Patients with malignant ascites gained efficient clinical therapeutic effects with chemotherapeutic intraperitoneal perfusion combined with local high freguency hyperthermia.
出处
《现代肿瘤医学》
CAS
2009年第6期1113-1114,共2页
Journal of Modern Oncology
关键词
灌注化疗
热疗
恶性腹水
chemotherapeutic perfusion
thermotherapy
malignant ascites