米非司酮配伍米索前列醇终止妊娠74例临床观察

Clinical observation of Mifepristone and Misoprostol for termination of 74 cases pregnancy

目的:观察米非司酮配伍米索前列醇终止10～14周妊娠的临床效果。方法:选择要求终止妊娠的孕10～14周的孕妇74例,米非司酮75mg,每日口服1次,连续2d,第3天上午口服米索前列醇600μg;若服米索前列醇2h后孕妇无宫缩,在阴道后穹隆置米索前列醇200μg。结果:61例服用米索前列醇后完全流产,7例需在阴道后穹隆放置米索前列醇200μg后才能完全流产,6例需行清宫术。结论:米非司酮配伍米索前列醇能安全有效终止10～14周妊娠。

Objective：To observe the clinical effects of mifepristone and misoprostol to terminate 10-14 weeks pregnancy. Methods： Seventy-four women of 10-14 weeks pregnancy who request termination of pregnancy, which receive orally 75 rag mifepristone once on the first and second day, followed orally 600 μg misoprostol in the morning of the third day; if pregnant women who receive misoprostol after 2 hour don＇t have uterine contractions, 200 μg misoprostol is placed in vaginal posterior fornix. Results： Sixty-one pregnant women can achieve complete abortion after orally misoprostol, seven pregnant women can also achieve complete abortion after placing 200 μg misoprostol in the vaginal posterior fornix and 6 pregnant women need Curettage to achieve abortion. Conclusion： Mifepristone and Misoprostol can be utilised to terminate 10-14 weeks pregrancy safely and effectively.